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KMID : 1161920150120020037
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Journal of Medicine and Life Science
2015 Volume.12 No. 2 p.37 ~ p.38
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Bilateral striopallidodentate calcinosis in a patient with myasthenia gravis
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Shin Ji-Yong
Kang Sa-Yoon
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Abstract
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Bilateral symmetric calcification involing striatum, pallidum with or without deposit in dentate nucleus is reported from asymptomatic individuals to a variety of neurological conditions. Clinically it may present with an array of movement disorders, dementia, cerebellar impairment and speech disorder. We report a myasthenia gravis patient with dysarthria which did not respond to pyridostigmin. Brain MRI showed bilateral striopallidodentate calcinosis (BSPDC). To our knowledge, there is no reported case having anti-acetylcholine receptor antibody and massive intracranial calcifications. This case indicates that BSPDC may develop in diverse neurological disorders.
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KEYWORD
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Anti-acetylcholine Receptor Antibody, Calcification, Myasthenia Gravis, MRI
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